EC313-a tissue selective SPRM reduces the growth and proliferation of uterine fibroids in a human uterine fibroid tissue xenograft model
نویسندگان
چکیده
منابع مشابه
The Ontario Uterine Fibroid Embolization Trial. Part 2. Uterine fibroid reduction and symptom relief after uterine artery embolization for fibroids.
OBJECTIVE To evaluate fibroid uterine volume reduction, symptom relief, and patient satisfaction with uterine artery embolization (UAE) for symptomatic fibroids. DESIGN Multicenter, prospective, single-arm clinical treatment trial. SETTING Eight Ontario university and community hospitals. Five hundred thirty-eight patients undergoing bilateral UAE. INTERVENTION(S) Bilateral UAE performed ...
متن کاملUterine fibroids: Correlations of anemia and pain to fibroid location and uterine weight.
OBJECTIVE To estimate the prevalence of anemia, pelvic pain and heavy vaginal bleeding among symptomatic women with and without submucosal fibroids who presented for uterine fibroid embolization (UFE), and to determine if uterine weight was related to patient reports of heavy bleeding and pelvic pain. STUDY DESIGN A case series study was performed that reviewed the ambulatory medical records ...
متن کامل[Uterine fibroid embolization in women with giant fibroids].
PURPOSE to evaluate the effectiveness of uterine fibroid embolization (UFE) in patients with giant fibroids, with regard to both clinical outcomes and size reduction. METHODS twenty-six patients with a mean age of 36.5 years, carrying symptomatic fibroids with a volume over 1,000 cm³, were referred for UFE. All patients had indication for percutaneous treatment. The procedures were performed ...
متن کاملA Large Uterine Fibroid
difficulties except those occasioned by the size of the tumour. The incision to deliver the tumour extended, from the pubes to the umbilicus and the weight and size of the tumour hindered considerably the subsequent steps of the operation. The broad ligaments which were greatly hypertrophied contained a large number of immense thin walled veins, some the size of the little finger, the ligation ...
متن کاملApplication of a Patient Derived Xenograft Model for Predicative Study of Uterine Fibroid Disease
Human uterine fibroids, benign tumors derived from the smooth muscle layers of the uterus, impose a major health burden to up to 50% of premenopausal women in their daily life. To improve our understanding of this disease, we developed and characterized a patient-derived xenograft model by subcutaneous transplantation of pieces of human uterine fibroid tissue into three different strains of sev...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-53467-w